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медицина
индекс ДНК
индекс содержания ДНК (в клетках опухоли)
общая лексика
ДНК
дезоксирибонуклеиновая кислота
(Distributed Internet Application) распределённые приложения Интернет, архитектура DNA
(Digital Network Architecture) архитектура цифровой сети
сетевая архитектура, разработанная корпорацией Digital Equipment. Реализована в сети DECnet
синоним
Смотрите также
существительное
общая лексика
архитектура цифровых сетей
синоним
['s(j)u:pəkɔil]
общая лексика
суперспираль
спираль второго порядка
синоним
DNA fragmentation is the separation or breaking of DNA strands into pieces. It can be done intentionally by laboratory personnel or by cells, or can occur spontaneously. Spontaneous or accidental DNA fragmentation is fragmentation that gradually accumulates in a cell. It can be measured by e.g. the Comet assay or by the TUNEL assay.
Its main units of measurement is the DNA Fragmentation Index (DFI). A DFI of 20% or more significantly reduces the success rates after ICSI.
DNA fragmentation was first documented by Williamson in 1970 when he observed discrete oligomeric fragments occurring during cell death in primary neonatal liver cultures. He described the cytoplasmic DNA isolated from mouse liver cells after culture as characterized by DNA fragments with a molecular weight consisting of multiples of 135 kDa. This finding was consistent with the hypothesis that these DNA fragments were a specific degradation product of nuclear DNA.